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Oxttm1.1(cre)Dolsn - Head
Recombinase Activity Detail
Allele Information
Allele:
Oxttm1.1(cre)Dolsn
oxytocin; targeted mutation 1.1, David P Olson 		Driver: Oxt
Type: Targeted (Recombinase)
Synonym: Oxytocin-Ires Cre
Molecular description: A targeting vector was designed to insert an IRES linked to cre recombinase, followed by a Frt-flanked kanamycin resistance gene downstream of the oxytocin (Oxt) stop codon. The construct was electroporated into 129S6/SvEvTac-derived W4 embryonic stem (ES) cells. Correctly targeted ES cells were injected into blastocysts and resulting chimeric mice were bred to flp expressing mice to delete the kanamycin selection cassette.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Oxttm1.1(cre)Dolsn activity also observed in:
nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Images
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J:192007 Fig. 1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 55 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory