Oxt<tm1.1(cre)Dolsn> - Nervous System Recombinase Activity Detail MGI Mouse

Oxt^{tm1.1(cre)Dolsn} - Nervous System
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Oxt^{tm1.1(cre)Dolsn}
oxytocin; targeted mutation 1.1, David P Olson

Driver: Oxt
Type: Targeted (Recombinase)

Synonym:

Oxytocin-Ires Cre

Molecular description:

A targeting vector was designed to insert an IRES linked to cre recombinase, followed by a Frt-flanked kanamycin resistance gene downstream of the oxytocin (Oxt) stop codon. The construct was electroporated into 129S6/SvEvTac-derived W4 embryonic stem (ES) cells. Correctly targeted ES cells were injected into blastocysts and resulting chimeric mice were bred to flp expressing mice to delete the kanamycin selection cassette.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Oxt^{tm1.1(cre)Dolsn} activity also observed in:
head

Tissue Information

Nervous System

Other recombinase alleles with activity in Nervous System tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acsm4^tm1(cre)Hsak, Adcyap1r1^{tm1.1(cre/GFP)Rpa} ...(more)

Images

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J:192007 Fig. 1

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

55 reference(s)

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