Tg(RHO-cre)1Qliu - Reproductive System Recombinase Activity Detail MGI Mouse

Tg(RHO-cre)1Qliu - Reproductive System
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Tg(RHO-cre)1Qliu
transgene insertion 1, Qinghuai Liu

Driver: RHO
Type: Transgenic (Recombinase)

Synonym:

Rho-Cre

Molecular description:

A vector containing the bovine rhodopsin promoter (RHO) and cre recombinase with a nuclear localization signal sequence was used for pronuclear injection of C57BL/6 x SJL oocytes. Nine transgenic founders were generated. RT-PCR analysis showed only retina-specific expression with no other positive tissue. The mice were crossed with Rosa26R-lacZ reporter animals to assess cre activity and specificity, with recombination (lacZ staining) detected specifically in rod photoreceptors.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Tg(RHO-cre)1Qliu activity also observed in:
head, sensory organs

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

1 reference(s)

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