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Tg(Cga-icre)961Sac - Liver & Biliary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Cga-icre)961Sac
transgene insertion 961, Sally A Camper 		Driver: Cga
Type: Transgenic (Recombinase)
Synonym: alphaGSU-iCre
Molecular description: A BAC (RP24-329P6) containing the Cga (alphaGSU) gene was modified by inserting a cassette composed of the sequence encoding a mammalian codon usage optimized cre recombinase (icre) and an Frt-flanked kanamycin selection marker, replacing the start codon in exon 2 of Cga with the ATG initiation codon of cre. Flpe excision removed the kanamycin selection marker. The modified BAC was injected into pronuclei of fertilized oocytes to generate transgenic mice. Line 961 was established.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Cga-icre)961Sac activity also observed in:
Images
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J:204533 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory