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Sohlh1tm1.1(cre/ERT2)Kliu - Reproductive System
Recombinase Activity Detail
Allele Information
Allele:
Sohlh1tm1.1(cre/ERT2)Kliu
spermatogenesis and oogenesis specific basic helix-loop-helix 1; targeted mutation 1.1, Kui Liu
Driver: Sohlh1
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Sohlh1-CreERT2
Molecular description: A targeting vector was constructed to insert a cre/ERT2-Frt-neo-Frt cassette into the Sohlh1 gene by homologous recombination. The cre cassette was inserted at the ATG start codon, replacing exons 1-8. Chimeras were bred to C57BL/6 mice, and F1 animals were crossed to flp-expressing mice to remove the neo marker.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Reproductive System Other recombinase alleles with activity in Reproductive System tissues:
Images
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J:206011 Fig. 3 J:206011 Fig. 4 J:206011 Fig. 5
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory