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Tg(Ucp1-cre)1Evdr - Endocrine System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Ucp1-cre)1Evdr
transgene insertion 1, Evan Rosen 		Driver: Ucp1
Type: Transgenic (Recombinase)
Synonym:
Molecular description: The C57BL/6 mouse bacterial artificial chromosome (BAC) 148M1 containing the entire Ucp1 gene, and other genes, was modified by inserting sequence encoding cre recombinase, into the translation initiation site into exon 1 of the Ucp1 gene. An FRT site flanked KAN cassette and a loxP site were removed. DNA from the modified BAC clone was used as the source for the transgene, which was microinjected into the pronucleus of FVB fertilized eggs. A founder line was subsequently established.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Ucp1-cre)1Evdr activity also observed in:
adipose tissue, head, integumental system, nervous system, renal & urinary system, reproductive system
Tissue Information
Endocrine System Other recombinase alleles with activity in Endocrine System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 103 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory