Calca<tm1.1(cre/EGFP)Rpa> - Nervous System Recombinase Activity Detail MGI Mouse

Calca^{tm1.1(cre/EGFP)Rpa} - Nervous System
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Calca^{tm1.1(cre/EGFP)Rpa}
calcitonin/calcitonin-related polypeptide, alpha; targeted mutation 1.1, Richard D Palmiter

Driver: Calca
Type: Targeted (Recombinase, Reporter)

Synonym:

Calca^Cre, CGRP^GFP

Molecular description:

The targeting vector used for homologous recombination contained a cre/GFP fusion sequence (cre fused in frame with EGFP at the C-terminus), N-terminal nuclear localization signal and myc tag, and frt-flanked PGK-neo marker. Cre was inserted at the initiation ATG codon in exon 2 of the gene. Chimeric animals were bred with Flper mice to remove the PGK-neo selection marker.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Calca^{tm1.1(cre/EGFP)Rpa} activity also observed in:
head

Tissue Information

Nervous System

Other recombinase alleles with activity in Nervous System tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acsm4^tm1(cre)Hsak, Adcyap1r1^{tm1.1(cre/GFP)Rpa} ...(more)

Images

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J:331457 Fig. 6

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

28 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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