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Tg(Prox1-cre/ERT2)1Tmak - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Prox1-cre/ERT2)1Tmak
transgene insertion 1, Taija Makinen 		Driver: Prox1
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Prox1-CreERT2, Tg(Prox1-cre/ERT2)#aTmak
Molecular description: The BAC clone RP23-190F21 is used to generate a transgene in which a cre/ERT2 fusion was inserted at the Prox1 start codon. Two founders were generated and the one (line 1) with complete recombination in all Prox1-expressing tissues was used for further studies.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Prox1-cre/ERT2)1Tmak activity also observed in:
hemolymphoid system, liver & biliary system
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:218590 Fig. 4 J:218590 Fig. S2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 68 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory