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Tg(Slc6a5-cre)1Uze - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Slc6a5-cre)1Uze
transgene insertion 1, University of Zurich 		Driver: Slc6a5
Type: Transgenic (Recombinase)
Synonym: GlyT2::Cre
Molecular description: The Cre coding sequence, with the bovine growth hormone polyadenylation signal, was inserted into the middle of exon 2 of the Sl6a5 gene in the BAC clone 365E4 from C57BL/6 BAC library RPCI-23. This BAC contains the entire coding sequence for both isoforms of the protein and 105 kb of 5' and 21 kb of 3' flanking genomic sequence. In transgenic mice, Cre expression is specific to neurons in the brain and spinal cord.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 7 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory