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Lhx9tm1.1(cre/ERT2)Gan - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Lhx9tm1.1(cre/ERT2)Gan
LIM homeobox protein 9; targeted mutation 1.1, Lin Gan 		Driver: Lhx9
Type: Targeted (Inducible, Null/knockout, Recombinase)
Inducer: tamoxifen
Synonym: Lhx9GCE, Lhx9-GFPCreERT2, Lhx9tm1.1(EGFP/cre/ERT2)Gan
Molecular description: The targeting construct replaced exon 4 with an EGFP, inducible cre recombinase fusion gene (EGFP/cre/ERT2) and an FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. The EGFP could not be detected by direct fluorescence or anti-GFP antibody staining. Expression of the EGFP/cre/ERT2 fusion protein is detected by anti-estrogen receptor antibody staining in adult retinal neurons.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Lhx9tm1.1(cre/ERT2)Gan activity also observed in:
head, limbs, reproductive system, sensory organs
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:214080 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory