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Tg(Sox10-icre/ERT2)388Wdr - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Sox10-icre/ERT2)388Wdr
transgene insertion 388, William D Richardson
Driver: Sox10
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Sox10-iCreERT2, Tg(Sox10-icre/ERT2)#aWdr
Molecular description: The transgene was generated using the PAC RP21-427F18. Oligodendrocyte-specific expression of the inducible improved cre recombinase (icre/ERT2) was achieved by replacing the coding sequence of Sox10 with the fusion. Four founders were obtained and one (388) was selected for further study.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Sox10-icre/ERT2)388Wdr activity also observed in:
alimentary system, branchial arches, head, mesenchyme, sensory organs
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:303671 Fig. 1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 26 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory