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Tektm1.1(icre/Esr1*)Hrr - Liver & Biliary System
Recombinase Activity Detail
Allele Information
Allele:
Tektm1.1(icre/Esr1*)Hrr
TEK receptor tyrosine kinase; targeted mutation 1.1, Hans-Reimer Rodewald
Driver: Tek
Type: Targeted (Inducible, Null/knockout, Recombinase)
Inducer: tamoxifen
Synonym: Tie2MCM, Tie2MCMdeltaNeo, Tie2MeriCreMer
Molecular description: The targeting cassette inserted into exon 1 upstream of the translation start site a rabbit HBB2 splice donor, intron and splice acceptor; an inducible improved cre fused to two modified Esr1 binding domains (icre/Esr1*); and an FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tektm1.1(icre/Esr1*)Hrr activity also observed in:
alimentary system, hemolymphoid system, skeletal system
Tissue Information
Liver & Biliary System Other recombinase alleles with activity in Liver & Biliary System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory