Tek<tm1.1(icre/Esr1*)Hrr> - Skeletal System Recombinase Activity Detail MGI Mouse

Tek^{tm1.1(icre/Esr1*)Hrr} - Skeletal System
Recombinase Activity Detail

Allele Information | Tissue Information | Recombinase Activity | References

Allele Information

Allele:

Tek^{tm1.1(icre/Esr1*)Hrr}
TEK receptor tyrosine kinase; targeted mutation 1.1, Hans-Reimer Rodewald

Driver: Tek
Type: Targeted (Inducible, Null/knockout, Recombinase)

Inducer:

tamoxifen

Synonym:

Tie2^MCM, Tie2^MCMdeltaNeo, Tie2^MeriCreMer

Molecular description:

The targeting cassette inserted into exon 1 upstream of the translation start site a rabbit HBB2 splice donor, intron and splice acceptor; an inducible improved cre fused to two modified Esr1 binding domains (icre/Esr1*); and an FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Tek^{tm1.1(icre/Esr1*)Hrr} activity also observed in:
alimentary system, hemolymphoid system, liver & biliary system

Tissue Information

Skeletal System

Other recombinase alleles with activity in Skeletal System tissues:

Acan^{tm1(cre/ERT2)Crm}, Agrp^tm1(cre)Lowl, Alpl^tm1(cre)Nagy, Alx3^{em1(cre/ERT2)Lanyu} ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

6 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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