Dcpp1<tm1.1(cre/ERT2)Ovi> - Renal & Urinary System Recombinase Activity Detail MGI Mouse

Dcpp1^{tm1.1(cre/ERT2)Ovi} - Renal & Urinary System
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Dcpp1^{tm1.1(cre/ERT2)Ovi}
demilune cell and parotid protein 1; targeted mutation 1.1, Catherine E Ovitt

Driver: Dcpp1
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Dcpp1-GCE, Dcpp1^GCE, Dcpp1-GFPCreErT2, Dcpp1^{tm1(cre/ERT2)Ovi}, Dcpp1^tm1(GCE)Ovi

Molecular description:

The EGFP-cre/ERT2 (GCE) fragment with an SV40 poly adenylation site and neomycin resistance cassette were inserted immediately downstream of the translational initiation codon ATG. The knock-in construct interrupted coding sequence in exon 2 and placed the GCE gene under the control of the endogenous regulatory sequences. Flp-mediated recombination removed the selection cassette. No expression of GFP was detected with fluorescence or using antibody to GFP. The fusion cre is expressed in intercalated duct cells of parotid gland and serous cells of sublingual gland.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Dcpp1^{tm1.1(cre/ERT2)Ovi} activity also observed in:
alimentary system

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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