Pip<tm1.1(cre/ERT2)Ovi> - Embryo-other Recombinase Activity Detail MGI Mouse

Pip^{tm1.1(cre/ERT2)Ovi} - Embryo-other
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Pip^{tm1.1(cre/ERT2)Ovi}
prolactin induced protein; targeted mutation 1.1, Catherine E Ovitt

Driver: Pip
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Pip ^GCE, Pip-GFP-CreERT2, Pip^tm2(GCE)Ovi

Molecular description:

The eGFP-CreERT2 (GCE) fragment with an SV40 poly adenylation site and neomycin resistance cassette were inserted immediately downstream of the translational initiation codon ATG. The knock-in construct removed the coding sequences from exon 1 and placed the GCE gene under the control of the endogenous regulatory sequences. Flp-mediated recombination removed the selection cassette. The EGFP could not be detected by direct fluorescence or anti-GFP antibody staining.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Pip^{tm1.1(cre/ERT2)Ovi} activity also observed in:
alimentary system

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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