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Tg(Six1-cre)2Kwk - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Six1-cre)2Kwk
transgene insertion 2, Kiyoshi Kawakami 		Driver: Six1
Type: Transgenic (Recombinase)
Synonym: mSix1-8-NLSCre, Six1enh8-Cre, Tg(Six1-enh8-cre)2Kwk
Molecular description: The transgene contains the sensory ganglion-specific enhancer of the Six1 homeobox gene (Six1enh8), the HSV thymidine kinase gene promoter, a chimeric intron a cre recombinase gene with a nuclear localization signal that are flanked by two tandem copies of the core region of the HS4 insulator. Lines 22L, 30L, 31L, 32L, 33L, 7l and 35l were generated. Line 35l is also designated as line 2 and was selected as the representative line.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Six1-cre)2Kwk activity also observed in:
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:227250 Fig. 4 J:227250 Fig. 5
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory