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Tg(Myh6-cre/ERT2/Hif1a)#Hhas - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Myh6-cre/ERT2/Hif1a)#Hhas
transgene insertion, Hesham A Sadek 		Driver: Myh6
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen and hypoxia
Synonym: alphaMHC-creERT2-ODD
Molecular description: The transgene contains the Myh6 promoter that drives cardiac-specific expression of the inducible cre recombinase gene (cre/ERT2) fused with the oxygen-dependent degradation (ODD) domain of Hif1a. This transgene is responsive to hypoxia. The pound symbol (#) is used when no line is specified and/or lines are pooled.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory