Npr3<em1(cre/ERT2)Bzsh> - Extraembryonic Component Recombinase Activity Detail MGI Mouse

Npr3^{em1(cre/ERT2)Bzsh} - Extraembryonic Component
Recombinase Activity Detail

Allele Information | Images | Recombinase Activity | References

Allele Information

Allele:

Npr3^{em1(cre/ERT2)Bzsh}
natriuretic peptide receptor 3; endonuclease-mediated mutation 1, Bin Zhou

Driver: Npr3
Type: Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Npr3-creER, Npr3^{tm1.1(cre/ERT2)Bz}, Npr3^{tm1.1(cre/ERT2)Bzsh}

Molecular description:

Using the CRISPR/Cas9 technology, a cDNA encoding cre/ERT2 followed by the Woodchuck Post-transcriptional regulatory element and a polyadenylation sequence was inserted in frame with the translational start codon of the Npr3 gene.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Npr3^{em1(cre/ERT2)Bzsh} activity also observed in:
cardiovascular system, cavities & their linings, mesenchyme

Images

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J:331898 Fig. 7

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

8 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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