Tacr1<tm1.1(cre/ERT2)Sros> - Head Recombinase Activity Detail MGI Mouse

Tacr1^{tm1.1(cre/ERT2)Sros} - Head
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Tacr1^{tm1.1(cre/ERT2)Sros}
tachykinin receptor 1; targeted mutation 1.1, Sarah E Ross

Driver: Tacr1
Type: Targeted (Inducible, Null/knockout, Recombinase)

Inducer:

tamoxifen

Synonym:

NK1R-CreER

Molecular description:

The coding region of Tacr1 in exon2 was replaced by a cre/ERT2 cassette and a loxP-flanked neo selection cassette by homologous recombination in ES cells. Correctly targeted ES cell clones were injected into C57BL/6 blastocysts. The neo-cassette was deleted by Cre-mediated excision.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Tacr1^{tm1.1(cre/ERT2)Sros} activity also observed in:
nervous system, sensory organs

Tissue Information

Head

Other recombinase alleles with activity in Head tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acan^{tm1(cre/ERT2)Crm}, Acsm4^tm1(cre)Hsak ...(more)

Images

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J:237538 Fig. 1

J:237538 Fig. 2

J:237538 Fig. 3

J:237538 Fig. 4

J:237538 Fig. 5

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

6 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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