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Tg(Stab2-icre)1.2Cger - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Stab2-icre)1.2Cger
transgene insertion 1.2, Cyrill Geraud 		Driver: Stab2
Type: Transgenic (Recombinase)
Synonym: Stab2-Cre, Stab2tg1.2cre
Molecular description: A cDNA containing a codon improved version of cre recombinase followed by polyA signal sequence was fused into BAC clone at exon 1 of mouse Stab2 gene so that cre expression is driven by the regulatory sequences of the BAC gene. The resulting modified BAC was used to generate this transgene. Three founder lines 1.1, 1.2, and 1.3 were identified. The line 1.2 displaying cre activity in liver sinusoidal endothelial cells were used for the study.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Stab2-icre)1.2Cger activity also observed in:
alimentary system, cardiovascular system, head, integumental system, liver & biliary system, mesenchyme
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:243226 Fig. 2 YFP
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory