Mrgprd<tm1.1(cre/ERT2)Wql> - Nervous System Recombinase Activity Detail MGI Mouse

Mrgprd^{tm1.1(cre/ERT2)Wql} - Nervous System
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Mrgprd^{tm1.1(cre/ERT2)Wql}
MAS-related GPR, member D; targeted mutation 1.1, Wenqin Luo

Driver: Mrgprd
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Molecular description:

A targeting construct was designed to insert a creERT2 fusion gene (a Cre recombinase fused to a human estrogen receptor ligand binding domain) followed by a frt-flanked neomycin resistance (neo) cassette, just downstream of the start codon of the MAS-related GPR, member D (Mrgprd) gene. Breeding to B6.129S4-Gt(ROSA)26Sor/J (Stock No. 007844) removed the neo cassette.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Mrgprd^{tm1.1(cre/ERT2)Wql} activity also observed in:
integumental system, limbs

Tissue Information

Nervous System

Other recombinase alleles with activity in Nervous System tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acsm4^tm1(cre)Hsak, Adcyap1r1^{tm1.1(cre/GFP)Rpa} ...(more)

Images

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J:245897 Fig. 1

J:245897 Fig. 2

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

18 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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