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Tg(Cacng5-cre)181Tjmc - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Cacng5-cre)181Tjmc
transgene insertion 181, Thomas J McHugh 		Driver: Cacng5
Type: Transgenic (Recombinase)
Synonym: Cacng5-Cre
Molecular description: The bacterial artificial chromosome (BAC) RP23-145G23 containing mouse calcium channel, voltagedependent, gamma subunit 5 (Cacng5) gene was modified to insert a Cre-FRT-Amp-FRT cassette at the start site of Cacng5 translation. The ampicillin (Amp) marker was deleted and the Cre-modified BAC's were confirmed, purified and injected into C57BL/6 fertilized pronuclei. Five founders (lines 160, 181, 190, 212, 225) were generated. The 181 Cacng5-Cre line was determined to express Cre selectively in the CA2 area of hippocampus using immunohistochemistry with the anti-Cre antibody, and used for analyses.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Cacng5-cre)181Tjmc activity also observed in:
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Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory