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Tg(Aldh1l1-cre/ERT2)02Kan - Respiratory System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Aldh1l1-cre/ERT2)02Kan
transgene insertion 02, Klaus-Armin Nave 		Driver: Aldh1l1
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Aldh1l1-CreERT2
Molecular description: The transgene was generated by inserting a cre/ERT2 cassette into intron 1/ exon 2 of the mouse Aldh1l1 in a murine BAC (BAC RP23-7M9) by homologous recombination in bacteria. Pronucleus injection gave rise to 5 transgenic founder mice. Three out of five founder mice that were crossed with reporter mice showed expression in the brain. Only one line (line 02) showed robust expression in forebrain astrocytic cells and minimal expression in other cell types of the brain and was used for further analyses.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Aldh1l1-cre/ERT2)02Kan activity also observed in:
alimentary system, head, liver & biliary system, nervous system, renal & urinary system
Tissue Information
Respiratory System Other recombinase alleles with activity in Respiratory System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory