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Tg(Chrna5-cre)3Et - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Chrna5-cre)3Et
transgene insertion 3, Eric E Turner 		Driver: Chrna5
Type: Transgenic (Recombinase)
Synonym: Chrna5BACCre, Chrna5Cre
Molecular description: A cre-expression cassette, followed by a polyadenylation sequence, was inserted into BAC clone RP24-318N16 at the initiating ATG codon of the first coding exon of the Chrna5 gene so that cre expression is driven by the regulatory sequences of the BAC gene. This BAC clone generated by the Gene Expression Nervous System Atlas (GENSAT) Project was furtehr subcloned to include only Chrna5 and deleting Chrna3 and Chrna4 genes on opposit strand of the original BAC clone. The resulting BAC was used to generate three independent lines. Transgenic line 3 was used for all analyses.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Chrna5-cre)3Et activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:264332 Fig. 4 J:264332 Fig. 5 J:264332 Fig. 5.1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory