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Brs3tm3.1(cre/ERT2)Rei - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Brs3tm3.1(cre/ERT2)Rei
bombesin-like receptor 3; targeted mutation 3.1, Marc L Reitman 		Driver: Brs3
Type: Targeted (Hypomorph, Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Brs3-2A-CreERT2, Brs3-Cre, BRS3-CreER
Molecular description: A targeting construct containing a 2A peptide, CreERT2 fusion gene, thymidine kinase polyadenylation signal sequence, followed by a FRT site flanked neo cassette was inserted into exon 3 of the targeted Brs3 gene into embryonic stem (ES) cells. The resulting chimeric animals were tested for germline transmission and were then bred to FLPo recombinase expressing mice to remove the neo cassette.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Brs3tm3.1(cre/ERT2)Rei activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:308449 Fig. 1 J:308449 Fig. 2 J:308449 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory