About   Help   FAQ
Tg(Slc6a4-cre)#Ito - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Slc6a4-cre)#Ito
transgene insertion, Shigeyoshi Itohara 		Driver: Slc6a4
Type: Transgenic (Recombinase)
Synonym: 5-HTTCre Tg, Tg(Slc6a4-cre)#Rerz
Molecular description: Tg construct was created by modifying the RP23-39F11 mouse BAC clone to insert the nuclear localization signal (NLS) Cre-pA cassette and FRT-Amp-FRT sequence into the translational initiation site of the Slc6a4 gene. The Amp sequence in the obtained BAC construct was removed by flp/FRT recombination in bacteria. The Tg founder mice were generated by microinjection of linearized constructs into C57BL/6 fertilized eggs. At least six lines were generated and two lines (208 and 810) were identified with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Slc6a4-cre)#Ito activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:216132 Fig. 1
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory