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Ly6gtm2621(cre)Arte - Hemolymphoid System
Recombinase Activity Detail
Allele Information
Allele:
Ly6gtm2621(cre)Arte
lymphocyte antigen 6 family member G; targeted mutation 2621, TaconicArtemis 		Driver: Ly6g
Type: Targeted (Null/knockout, Recombinase, Reporter)
Synonym: Ly6gtm1.1(cre)Gunz, Ly6gtm2621(cre,-tdTomato)Arte, Ly6g(tm2621(CretdTomato)Arte
Molecular description: The Ly6g coding sequence in exon 1 and the splice donor site at the junction of exon 1 and intron 1 were replaced with a cassette containing the open reading frame of Cre recombinase and tdTomato separated by a self-splicing T2A peptide. A human growth hormone polyadenylation signal was inserted at the 3' end of the Cre-T2A-tdTomato sequence in order to prevent downstream transcription of the remaining mouse Ly6g. The FRT flanked positive selection marker (puromycin resistance (PuroR)) was removed after the successful generation of transgenic mice by crossing with Flpe expressing mice.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Ly6gtm2621(cre)Arte activity also observed in:
mouse-other, skeletal system
Tissue Information
Hemolymphoid System Other recombinase alleles with activity in Hemolymphoid System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 32 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory