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Tg(Tbx6-cre)#Rsam - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Tbx6-cre)#Rsam
transgene insertion, Ramkumar Sambasivan 		Driver: Tbx6
Type: Transgenic (Recombinase)
Synonym: Tbx6-Cre
Molecular description: Using a bacterial artificial chromosome (BAC), transgene was created such that the cre recombinase is driven by Tbx6 regulatory sequences. The Cre recombinase expression cassette was inserted into into a bacterial artificial chromosome (BAC; clone# RP24239G12) containing Tbx6 locus with approximately 84 Kb upstream, 4 Kb of the open reading frame and 73 Kb downstream sequences at the 1st exon of Tbx6 such that 14 nucleotides (25th to 39th bases) including the ATG are removed. Four lines were generated with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Tbx6-cre)#Rsam activity also observed in:
alimentary system, embryo-other, limbs, mesenchyme, mouse-other, tail
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:274134 Fig. 3 J:274134 Fig. S4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory