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Dmrt3em1(cre)Kldr - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Dmrt3em1(cre)Kldr
doublesex and mab-3 related transcription factor 3; endonuclease-mediated mutation 1, Klas Kullander
Driver: Dmrt3
Type: Endonuclease-mediated (Recombinase)
Synonym: Dmrt3Cre
Molecular description: Zinc finger nuclease mRNAs designed for the Dmrt3 locus, and a donor vector carrying iCre and 2A peptide sequence were introduced to B6D2F1 zygotes by pronuclear microinjection. The 2A peptide coding sequence allows for cotranslation of the Dmrt3 promoter-driven iCre followed by Dmrt3.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Dmrt3em1(cre)Kldr activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:273477 Fig. 1 J:273477 Fig. 1-1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory