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Tg(Elf5-cre/ERT2,-GFP)2Rcha - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Elf5-cre/ERT2,-GFP)2Rcha
transgene insertion 2, Rumela Chakrabarti 		Driver: Elf5
Type: Transgenic (Inducible, Recombinase, Reporter)
Inducer: tamoxifen
Synonym: Elf5CreERT2-GFP
Molecular description: A partial coding sequence of exon 2 of Elf5 was replaced with CreERT2-P2A-eGFP-SV40pA-Frt-Neo cassette-Frt by homologous recombination into BAC clone RP23-44A14. The Neo cassette flanked by Frt sites was deleted after FLP-mediated recombination. Six lines were generated and three lines with GFP expression in the mammary glands were kept for the initial screening. Line 2 and 5 showed strong GPF and essentially identical cre activity after tamoxifen induction. Line 2, male founder was selected for the detailed analysis.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Elf5-cre/ERT2,-GFP)2Rcha activity also observed in:
alimentary system, renal & urinary system, reproductive system, respiratory system
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory