Pdx1<tm1.1(dre)Gkg> - Alimentary System Recombinase Activity Detail MGI Mouse

Pdx1^{tm1.1(dre)Gkg} - Alimentary System
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Pdx1^{tm1.1(dre)Gkg}
pancreatic and duodenal homeobox 1; targeted mutation 1.1, George K Gittes

Driver: Pdx1
Type: Targeted (Recombinase)

Synonym:

Pdx1-Dre

Molecular description:

The targeting construct was generated such that exon 2 of the mouse Pdx1 gene in a BAC clone RP23-59N19 was replaced with a modified exon 2 in which a 2A peptide sequence followed by the Dre sequence was inserted immediately before the stop codon of the Pdx1-coding sequence. The FRT-flanked neomycin selection cassette (neo) was placed at the beginning of the 3' untranslated sequence which was removed by crossing chimeric mice with Flpo mice.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Pdx1^{tm1.1(dre)Gkg} activity also observed in:
endocrine system

Tissue Information

Alimentary System

Other recombinase alleles with activity in Alimentary System tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, A4gnt^{tm1.1(cre/ERT2)Niba}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Agrp^tm1(cre)Lowl ...(more)

Images

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J:278248 Fig. 2

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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