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Wt1em1(cre/ERT2)Bzsh - Cavities & Their Linings
Recombinase Activity Detail
Allele Information
Allele:
Wt1em1(cre/ERT2)Bzsh
WT1 transcription factor; endonuclease-mediated mutation 1, Bin Zhou 		Driver: Wt1
Type: Endonuclease-mediated (Conditional ready, Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Wt1-CrexER
Molecular description: The mouse line was generated by homologous recombination using the CRISPR/Cas9 technology. A complementary DNA encoding Cre recombinase fused with 2 rox sequences flanking a mutant form of the ESR hormone-binding domain (ERT2) was inserted into the translational start site of the Wt1 gene and followed by a polyadenylation sequence.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Wt1em1(cre/ERT2)Bzsh activity also observed in:
cardiovascular system, mesenchyme
Tissue Information
Cavities & Their Linings Other recombinase alleles with activity in Cavities & Their Linings tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory