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Tg(Pdgfrb-FLP1,Cspg4-cre/ERT2)#Bvz - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Pdgfrb-FLP1,Cspg4-cre/ERT2)#Bvz
transgene insertion, Berislav V Zlokovic 		Driver: Cspg4
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Pdgfrb-Flp;Cspg4-FSF-CreER
Molecular description: Two constructs consisting of one with a mouse Pdgfrb promotor driving Flp recombinase and another carring a Frt-Stop-Frt-CreERT2 cassette under the control of the mouse Cspg4 promoter were co-injected into C57BL/6 blastocysts via pronuclear injection. Five founder pups were identyfied as carrying both transgenes. One unnamed founder line was established and verified. The pound symbol (#) is used when no line name is specified and/or lines are pooled.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pdgfrb-FLP1,Cspg4-cre/ERT2)#Bvz activity also observed in:
head, nervous system
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory