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Slc17a8em1(icre/ERT2)Zyliu - Head
Recombinase Activity Detail
Allele Information
Allele:
Slc17a8em1(icre/ERT2)Zyliu
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8; endonuclease-mediated mutation 1, Zhiyong Liu 		Driver: Slc17a8
Type: Endonuclease-mediated (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: vGlut3-P2A-iCreER
Molecular description: A plasmid encoding a guide RNA and PAM sequence TGG was designed to introduce a P2A peptide fused to an icre/ERT2 cassette into exon 12, immediately before the stop codon, of the solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 (Slc17a8) gene. Guide RNA and the cas9 nuclease were introduced into the cytoplasm of C57BL/6N-derived fertilized eggs with well recognized pronuclei.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Slc17a8em1(icre/ERT2)Zyliu activity also observed in:
sensory organs
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory