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Tnni3em1(dre)Bzsh - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tnni3em1(dre)Bzsh
troponin I, cardiac 3; endonuclease-mediated mutation 1, Bin Zhou 		Driver: Tnni3
Type: Endonuclease-mediated (Recombinase)
Synonym: Tnni3-Dre
Molecular description: A cDNA encoding Dre recombinase was iserted into the site encoding the translational start codon of the Krt19 gene, using the CRISPR/Cas9 technology. The woodchuck hepatitis virus post-transcriptional regulatory element (WPRE) were placed after the Dre cDNA sequence to stabilize the Dre-encoding mRNA.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory