Ndnf<tm1.1(cre/ERT2)Ispgl> - Nervous System Recombinase Activity Detail MGI Mouse

Ndnf^{tm1.1(cre/ERT2)Ispgl} - Nervous System
Recombinase Activity Detail

Allele Information | Tissue Information | Recombinase Activity | References

Allele Information

Allele:

Ndnf^{tm1.1(cre/ERT2)Ispgl}
neuron-derived neurotrophic factor; targeted mutation 1.1, Ivo Spiegel

Driver: Ndnf
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Ndnf-IRES-CreERT2

Molecular description:

The targeting vector was designed to insert an internal ribosome entry site (IRES) fused to a Cre/ERT2 fusion gene (Cre recombinase fused to a human estrogen receptor ligand binding domain) into the 3' UTR in exon 4 of the neuron-derived neurotrophic factor (Ndnf) gene. The construct also included a frt-flanked neomycin resistance cassette. After homologouse recombination in ES cells, the resulting chimeric mice were bred with flp recombinase expressing mice to remove the neo cassette.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Ndnf^{tm1.1(cre/ERT2)Ispgl} activity also observed in:
head

Tissue Information

Nervous System

Other recombinase alleles with activity in Nervous System tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acsm4^tm1(cre)Hsak, Adcyap1r1^{tm1.1(cre/GFP)Rpa} ...(more)

Recombinase Activity

Click heading to re-sort table.

Assays Genotypic Background Result Notes

References

All for this allele:

4 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24