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Oprm1tm1.1(cre/GFP)Rpa - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Oprm1tm1.1(cre/GFP)Rpa
opioid receptor, mu 1; targeted mutation 1.1, Richard D Palmiter 		Driver: Oprm1
Type: Targeted (Null/knockout, Recombinase, Reporter)
Synonym: Oprm1Cre, Oprm1Cre:GFP
Molecular description: A cassette encoding Cre:GFP (a Myc-tag and nuclear localization signals at the N-terminus of Cre recombinase, which is fused to green fluorescent protein followed by a SV40 polyadenylation sequence) was inserted just 5' of the initiation codon in the first coding exon of the Oprm1 gene replacing the exon 1 via homologous recombination. The neomycin cassette was excised of through crosses with animals broadly expressing Flp recombinase.
Collection: Sanger miRNA knockouts
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Oprm1tm1.1(cre/GFP)Rpa activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:314358 Fig. 4 J:314358 Fig. S1 J:331457 Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 7 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory