Smoc2<tm1(cre/ERT2)Cle> - Nervous System Recombinase Activity Detail MGI Mouse

Smoc2^{tm1(cre/ERT2)Cle} - Nervous System
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Smoc2^{tm1(cre/ERT2)Cle}
SPARC related modular calcium binding 2; targeted mutation 1, Hans Clevers

Driver: Smoc2
Type: Targeted (Inducible, Recombinase, Reporter)

Inducer:

tamoxifen

Synonym:

Smoc2-EGFP-ires-CreERT2

Molecular description:

An EGFP-IRES-creERT2 cassette was inserted at the translational start site of the gene along with a loxP-flanked neomycin cassette. The neomycin gene was then excised in vivo by crossing with a cre-deleter strain. EGFP expression is driven by the endogenous promoter. Cre expression is induced in Smoc2 expressing cells by tamoxifen treatment.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Smoc2^{tm1(cre/ERT2)Cle} activity also observed in:
alimentary system, head, integumental system, mesenchyme, sensory organs

Tissue Information

Nervous System

Other recombinase alleles with activity in Nervous System tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acsm4^tm1(cre)Hsak, Adcyap1r1^{tm1.1(cre/GFP)Rpa} ...(more)

Images

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J:296149 Fig. S2

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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