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Lgr5tm3.1(cre/ERT2)Niba - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Lgr5tm3.1(cre/ERT2)Niba
leucine rich repeat containing G protein coupled receptor 5; targeted mutation 3.1, Nick Barker 		Driver: Lgr5
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Lgr5-2A-creERT2
Molecular description: Sequence for the 2A self-cleaving peptide, a cre-ERT2 fusion gene and a loxP site flanked neomycin resistance gene cassette were inserted immediately before the stop codon. The neo cassette was removed through subsequent cre-mediated recombination. This allele expresses the endogenous peptide and the inserted cre-ERT2 fusion peptide.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Images
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J:319855 Fig. S1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory