Foxl1<tm2(cre/ERT2)Khk> - Liver & Biliary System Recombinase Activity Detail MGI Mouse

Foxl1^{tm2(cre/ERT2)Khk} - Liver & Biliary System
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Foxl1^{tm2(cre/ERT2)Khk}
forkhead box L1; targeted mutation 2, Klaus H Kaestner

Driver: Foxl1
Type: Targeted (Inducible, Null/knockout, Recombinase, Reporter)

Inducer:

tamoxifen

Synonym:

Foxl1CreERT2-2A-tdTomato, FoxL1^CreER-tdTom

Molecular description:

The targeting vector contains a Cre recombinase/ERT2 fusion, a viral 2A oligopeptide that mediates ribosomal skipping, and a tdTomato reporter followed by neomycin resistance cassette inserted after the ATG site in exon 1. The insertion deletes 200 bp of the coding sequence rendering the allele null.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Foxl1^{tm2(cre/ERT2)Khk} activity also observed in:
alimentary system

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

3 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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