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Zfp683tm1.1(cre,Hbegf)Kgis - Mouse-other
Recombinase Activity Detail
Allele Information
Allele:
Zfp683tm1.1(cre,Hbegf)Kgis
zinc finger protein 683; targeted mutation 1.1, Klaas van Gisbergen 		Driver: Zfp683
Type: Targeted (Inserted expressed sequence, Null/knockout, Recombinase, Reporter)
Synonym: B6-Tg(Zfp683-tdTomato-P 2A-Cre-P2A-DTR, Zfp683tm1.1(cre,DTR)Kgis
Molecular description: Homologous recombination in ES cells targeted to insert the fluorescent protein tdTomato, cre recombinase and the diphtheria toxin receptor (DTR) separated by P2A sequences (tdTomato-P2A-Cre-P2A-DTR) into the endogenous Zfp683 locus whereby the targeting sequence replaced exons 2, 3 and 4, as well as intronic sequences of the Zfp683 gene (knockin knockout). An FRT-flanked neomycin resistance gene was also introduced. Embryonic stem cell-derived offspring were then bred with FLPO mice to remove neo selection cassette.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Mouse-other Other recombinase alleles with activity in Mouse-other tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory