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Oprm1tm1.1(cre/ERT2)Dwata - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Oprm1tm1.1(cre/ERT2)Dwata
opioid receptor, mu 1; targeted mutation 1.1, Dai Watanabe 		Driver: Oprm1
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: MOR-CreER
Molecular description: A bacterial artificial chromosome (BAC) containing the mouse Oprm1 gene (RP24-112H16) was modified so that the translational stop codon in exon 4 of the Oprm1 gene was replaced by a cassette comprising the T2A sequence, icre/ERT2 gene with stop codon and FRT-flanked neomycin-resistant gene (T2A-iCreERT2-FRT-Neo-FRT). The homologous recombination in the mouse ES cells generated a chimeric mouse which was crossed with CAG-FLPe mice to remove the FRT-flanked neomycin resistance cassette in the offspring.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Oprm1tm1.1(cre/ERT2)Dwata activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:302775 Fig. 1 J:302775 Fig. 2 J:302775 Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory