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Tg(Csf2rb2-cre)252Tjmc - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Csf2rb2-cre)252Tjmc
transgene insertion 252, Thomas J McHugh 		Driver: Csf2rb2
Type: Transgenic (Recombinase)
Synonym: Csf2rb2-Cre, SuM-Cre
Molecular description: The bacterial artificial chromosome (BAC) RP23-233L7 containing mouse the colony stimulating factor 2 receptor, beta2 (Csf2rb2) gene was modified to insert a Cre-FRT-Amp-FRT cassette at the start site of Csf2rb2 translation. The ampicillin (Amp) marker was deleted and the Cre-modified BAC's were confirmed, purified, and injected into C57BL/6 fertilized pronuclei. Four founders (lines 252, 267, 271, 272) were generated. The line 252 Csf2rb2-Cre line was determined to express Cre selectively supramammillary area of the hypothalamus using immunohistochemistry with the anti-Cre recombinase antibody, and used for analyses.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Csf2rb2-cre)252Tjmc activity also observed in:
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Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory