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Tg(Tbx21-cre)1Yyos - Head
Recombinase Activity Detail
Allele Information
Allele:
Tg(Tbx21-cre)1Yyos
transgene insertion 1, Yoshihiro Yoshihara 		Driver: Tbx21
Type: Transgenic (Recombinase)
Synonym: Cla-Cre
Molecular description: The transgene consisting of the 5.0-kb upstream enhancer/promoter region sequence of the mouse Tbx21 gene was fused to the bacteriophage P1 Cre recombinase gene with the human -globin gene intron and simian virus 40 polyadenylation signal driving cre expression specifically in the mitral/tufted cells of the olfactory bulb. The DNA construct was purified and initialized then injected into the pronucleus of fertilized eggs that were obtained from crossing C57BL/6J and DBA/2J mice. Seven transgenic mouse lines were established and one (line no. 1) showed ectopic expression of Cre protein specifically in the claustrum and was used for the study.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Tbx21-cre)1Yyos activity also observed in:
nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory