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Cdkn2atm2.1(cre/ERT2)Dvb - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Cdkn2atm2.1(cre/ERT2)Dvb
cyclin dependent kinase inhibitor 2A; targeted mutation 2.1, Dmitry V Bulavin 		Driver: Cdkn2a
Type: Targeted (Inducible, Recombinase, Reporter)
Inducer: tamoxifen
Synonym: p16-CreERt2
Molecular description: An T2A-Cre/ERT2-T2A-TK-T2A-mCherry cassette was introduced at the end of the last exon of the Cdkn2a (p16Ink4) gene by homologous recombination in the ES cells. The Frt-loxed Neo cassette was removed by crossing with FLP deleter.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Cdkn2atm2.1(cre/ERT2)Dvb activity also observed in:
liver & biliary system
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory