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Tg(Relb-cre)53Rie - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Relb-cre)53Rie
transgene insertion 53, Marc Riemann 		Driver: Relb
Type: Transgenic (Recombinase, Reporter)
Synonym: RelbCre-Kat, Relb-Cre-P2A-Katushka
Molecular description: The transgene consists of a bacterial artificial chromosome (BAC) of 93 kb (bMQ-258 k08) containing the complete Relb locus with 45 kb of upstream region was modified by introducing the gene coding for a Cre recombinase and Katushka, both linked by a self-cleaving P2A peptide into the first exon of the Relb gene just downstream of the translation initiation codon. Katushka (TurboFP635) is a far-red mutant of the red fluorescent protein from sea anemone Entacmaea quadricolor. Four founder mice were obtained, which transmitted the transgene to the progeny. In one of these founder lines (#53) transgene expression reflected that of endogenous Relb which was used for further study.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Relb-cre)53Rie activity also observed in:
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:292655 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory