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Pdgfrbtm1.2(flpo)Leol - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Pdgfrbtm1.2(flpo)Leol
platelet derived growth factor receptor, beta polypeptide; targeted mutation 1.2, Lorin E Olson 		Driver: Pdgfrb
Type: Targeted (Null/knockout, Recombinase)
Synonym: bRdeltaFlp, PdgfrbdetalFlp
Molecular description: The targeting cassette consisting of a SA.lox.PDGFRb.lox-Flpo-attB-Neo-attP cassette replaced the exons 2-4 of the endogenous Pdgfrb gene. The PDGFRb is a mouse Pdgfrb gene cDNA. PhiC31 integrase removed the attB-Neo-attP cassette. Cre-mediated recombination removed lox.PDGFRb.lox cassette from Pdgfrbtm1.1(flpo)Leol to enable the expression of the flpo recombinase. This is a nock-in-nock-out null allele.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Pdgfrbtm1.2(flpo)Leol activity also observed in:
adipose tissue
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory