Il17a<tm2.1(EGFP/cre/ERT2)Flv> - Alimentary System Recombinase Activity Detail MGI Mouse

Il17a^{tm2.1(EGFP/cre/ERT2)Flv} - Alimentary System
Recombinase Activity Detail

Allele Information | Tissue Information | Recombinase Activity | References

Allele Information

Allele:

Il17a^{tm2.1(EGFP/cre/ERT2)Flv}
interleukin 17A; targeted mutation 2.1, Richard A Flavell

Driver: Il17a
Type: Targeted (Inducible, Recombinase, Reporter)

Inducer:

tamoxifen

Synonym:

IL-17A IRES-eGFP-CRE-ERT2

Molecular description:

A cassette encoding for a fusion protein consisting of the Internal Ribosome Entry Site (IRES), eGFP, Cre and human-modified Oestrogen Receptor (ERT2) (IGCE) was linked to a Frt-flanked neomycin (NEO) encoding cassette and inserted downstream of the translation stop codon in the mouse Il17a gene by targetted homologous recombination in ES cells. Germline transmitted mice were bred with germline Flippase expressing transgenic mice to remove the neomycin gene.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Il17a^{tm2.1(EGFP/cre/ERT2)Flv} activity also observed in:
mouse-other

Tissue Information

Alimentary System

Other recombinase alleles with activity in Alimentary System tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, A4gnt^{tm1.1(cre/ERT2)Niba}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Agrp^tm1(cre)Lowl ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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