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Tg(KRT5-cre/ERT2)2Blh - Respiratory System
Recombinase Activity Detail
Allele Information
Allele:
Tg(KRT5-cre/ERT2)2Blh
transgene insertion 2, Brigid L Hogan 		Driver: KRT5
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: KRT5- CreERT
Molecular description: The 6-kb human keratin 5 (KRT5) promoter drives a cre/ERT2 cassette. The cre/ERT2 is flanked by an intron and a polyadenylation sequence from the pCI mammalian expression vector. The construct was injected into fertilized zygotes. 11 founder lines were obtained, and 2nd line that has expression in esophageal basal cells but not in tracheal cells was established.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(KRT5-cre/ERT2)2Blh activity also observed in:
alimentary system
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory