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Allele Information
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Allele:
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Cacna1htm2.1(cre)Glwn
calcium channel, voltage-dependent, T type, alpha 1H subunit;
targeted mutation 2.1, Gary R Lewin
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Driver: Cacna1h
Type: Targeted
(Null/knockout, Recombinase)
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Synonym:
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Cav3.2Cre
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Molecular description:
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Targeting vectors to insert cre expression cassette after the start codon of the Cacna1h (Cav3.2) gene located at the second exon was used to generate the allele by homologous recombination in ES cells. The insertion of the cre cassettes produces a null mutation of the Cacna1h gene. The neo cassette was removed by flpe recombinase.
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Find mice (IMSR):
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Mouse Strains:
0 strains available
Cell Lines:
0 lines available
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Additional Tissues:
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Cacna1htm2.1(cre)Glwn activity also observed in:
head,
integumental system,
limbs,
nervous system,
skeletal system
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Tissue Information
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Muscle
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Other recombinase alleles with activity in Muscle tissues:
A1cfTg(Myh6-cre/Esr1*)1Jmk,
Abcg2tm1.1(cre/Esr1*)Jvbe,
Acantm1(cre/ERT2)Crm,
Aldh1l1em1(cre/ERT2)Nju,
Alpltm1(cre)Nagy,
Aplntm1.1(cre/ERT2)Bzsh,
Atoh8tm1(EGFP/cre)Gasa,
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Cdh5em1(cre/ERT2)Smoc,
Chattm2(cre)Lowl,
Clutm2(EGFP/cre/ERT2)Wtsi,
Commd10Tg(Vav1-icre)A2Kio,
Dmp1tm1(cre)Msue,
E2f1Tg(Wnt1-cre)2Sor,
Emx1tm1(cre)Krj,
En1tm2(cre)Wrst,
Etv1tm1.1(cre/ERT2)Zjh,
Foxa2tm2.1(cre/Esr1*)Moon,
Foxd1tm1(GFP/cre)Amc,
Gad2tm2(cre)Zjh,
Gjd3tm1.1(cre/EGFP)Nmun,
Gli1tm3(cre/ERT2)Alj,
Gnao1tm2(EGFP/cre/ERT2)Wtsi,
Gt(ROSA)26Sorem1(CAG-Ncre/vvd*,-vvd*/Ccre)Larc,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm1(FLP1)Dym,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
Gt(ROSA)26Sortm8(CAG-dre/ERT2)Bzsh,
H2az2Tg(Wnt1-cre)11Rth,
Hand1tm1.1(EGFP/cre)Abfi,
Hcn4tm1(cre/ERT2)Anlu,
HhatTg(TFAP2A-cre)1Will,
Hic1tm2.1(cre/ERT2)Tmun,
Hprt1tm1(CAG-cre)Mnn,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Hsd11b2tm1(cre)Anft,
Ifi208Tg(Cspg4-cre)1Akik,
Igs2tm1(Cdkn1a-cre/ERT2,-EGFP)Mxu,
Igs2tm2(Smarcd3-cre/ERT2)Bbr,
Isl1tm1(cre/Esr1*)Krc,
Isl1tm1(cre)Sev,
Isl1tm1(cre)Tmj,
Kdrtm1(cre)Sato,
Kittm1.1(cre)Jmol,
Krt17tm1(cre)Murr,
Leprtm2(cre)Rck,
Lyve1tm1.1(EGFP/cre)Cys,
Lyz2tm1(cre)Ifo,
Mgptm1.1(cre)Borr,
Mnx1tm4(cre)Tmj,
Myf5tm1.1(cre/Esr1*)Trdo,
Myf5tm1.1(cre)Mrc,
Myf5tm1(cre/Esr1*)Trdo,
Myf5tm1(cre)Mrc,
Myf5tm3(cre)Sor,
Myf6tm1.1(cre/ERT2)Lepr,
Myf6tm1.1(cre/Esr1*)Cklr,
Myf6tm1(cre)Mrc,
Myf6tm2(cre)Mrc,
Myh6em2(cre)Smoc,
Myl1tm1.1(cre/ERT2)Lepr,
Myl2tm1(cre)Krc,
Myocdtm1(cre)Dzw,
Myocdtm1(cre)Jomm,
Myod1tm1.1(cre/ERT2)Lepr,
Myod1tm2.1(icre)Glh,
Myogtm1.1(cre/ERT2)Lepr,
Ndor1Tg(UBC-cre/ERT2)1Ejb,
Nfatc1em4(cre/ERT2)Bzsh,
Nfatc1tm1.1(cre/ERT2)Bzsh,
Nkx2-5tm1(cre)Rjs,
Nkx2-5tm2(cre)Rph,
Nos1tm1.1(cre/ERT2)Zjh,
Notch1tm3(cre)Rko,
Omptm4(cre)Mom,
Oprk1tm1.1(cre)Sros,
Osr2tm2(cre)Jian,
P2rx2tm1.1(cre)Ttc,
Pax3tm1.1(cre/ERT2)Lepr,
Pax3tm1(cre)Joe,
Pax7tm1(cre/ERT2)Gaka,
Pax7tm1(cre/Esr1*)Cklr,
Pax7tm1(cre)Mrc,
Pax7tm2.1(cre/ERT2)Fan,
Pbx3tm1(EGFP/cre/ERT2)Wtsi,
Pdgfratm1.1(cre/ERT2)Trdo,
Pdgfratm1.1(EGFP/cre/ERT2)Hyma,
Pdgfrbtm1.1(cre/ERT2)Csln,
Pitx2tm4(cre)Jfm,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Pms2tm2(cre)Lisk,
Pvalbtm1(cre)Arbr,
Runx3tm1(flpo)Noo,
Scxtm1.1(cre)Shuk,
Sema3atm1.1(cre/ERT2)Bzsh,
Shhtm1(EGFP/cre)Cjt,
Shroom3Gt(ROSA53)Sor,
Sptbtm2(EGFP/cre/ERT2)Wtsi,
Ssttm2.1(cre)Zjh,
Taglntm1(cre/ERT2)Feil,
Taglntm2(cre)Yec,
Tbx1tm6(cre)Bld,
Tcf7l2tm3.1(cre/ERT2)Mrc,
Tg(ACTA1-cre)1Mll,
Tg(ACTA1-cre)79Jme,
Tg(ACTA1-cre/ERT2)97.16Mtz,
Tg(ACTA1-cre/Esr1*)2Kesr,
Tg(ACTA1-rtTA,tetO-cre)102Monk,
Tg(Acta2-cre/ERT2)12Pcn,
Tg(Acta2-cre/ERT2)1Ikal,
Tg(Acta2-cre/ERT2)51Pcn,
Tg(ACTC1-cre)1Miwa,
Tg(Alb1-cre)1Dlr,
Tg(Bmx-cre/ERT2)1Rha,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(CAG-cre/Esr1*)86Lbgn,
Tg(Camk2a-cre/ERT2)1Aibs,
Tg(CD2-icre)4Kio,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(CDX2-cre)101Erf,
Tg(Cga-cre)3Sac,
Tg(Ckmm-cre)5Khn,
Tg(CMV-cre)1And,
Tg(CMV-cre)1Cgn,
Tg(COL2A1-cre)1Wag,
Tg(Col6a1-cre)1Gkl,
Tg(Colq-cre)#Kohno,
Tg(Csf1r-icre)1Jwp,
Tg(Cspg4-cre/Esr1*)BAkik,
Tg(Csrp1-cre)1Sjc,
Tg(Ctgf-cre)2Aibs,
Tg(Cyp1a1-cre)1Dwi,
Tg(Cyp39a1-cre)1Aibs,
Tg(Dct-cre)1Apdn,
Tg(Ddx4-cre)1Dcas,
Tg(dlx5a-cre)1Mekk,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)39Jme,
Tg(Fabp4-cre)1Abel,
Tg(Fabp4-cre)1Rev,
Tg(Fabp4-cre/ERT2)1Ipc,
Tg(Fgfr3-icre/ERT2)4-2Wdr,
Tg(Gabra6-cre)B1Lfr,
Tg(Gata1-cre)1Sho,
Tg(GATA5-cre)1Krc,
Tg(GATA6-cre)#Jbeb,
Tg(GFAP-cre)25Mes,
Tg(Gfap-cre)73.12Mvs,
Tg(Gfap-cre)77.6Mvs,
Tg(Gjb6-cre/ERT2)53-33Fwp,
Tg(Glp1r-icre)#Fmgb,
Tg(Grik4-cre)G32-4Stl,
Tg(Hand1-EGFP/cre)#Abfi,
Tg(Hoxb8-cre)1403Uze,
Tg(Hspa2-cre)1Eddy,
Tg(Ins2-cre)25Mgn,
Tg(Islr-cre/ERT2)#Tobe,
Tg(Itgax-cre)1-1Reiz,
Tg(Kcne1-cre/ERT2)1Imos,
Tg(KRT14-cre)1Amc,
Tg(Mef2c-cre)1Blk,
Tg(Mef2c-cre)2Blk,
Tg(Mef2c-cre)#Blk,
Tg(MMTV-cre)4Mam,
Tg(Mx1-cre)1Cgn,
Tg(Myh11-cre)5013Gko,
Tg(Myh11-cre,-EGFP)2Mik,
Tg(Myh11-cre/ERT2)F31Gko,
Tg(Myh11-dre/ERT2)#Cya,
Tg(Myh11-icre/ERT2)1Soff,
Tg(Myh6-cre)1Xya,
Tg(Myh6-cre)2182Mds,
Tg(Myh6-cre/PGR*)1Mds,
Tg(Myh6-cre/PGR*)6297Mds,
Tg(Myh7-cre)1Zli,
Tg(Myl1-cre)13Nros,
Tg(myl7.L-cre)1118Tmhn,
Tg(MYOD1-cre)M23Glh,
Tg(Myog-cre)1Eno,
Tg(Nes-cre)1Atp,
Tg(Nes-cre)1Kln,
Tg(Nkx2-5-cre)9Eno,
Tg(Nppa-cre)3Vmc,
Tg(Opn4-cre)#Yau,
Tg(Osr1-cre)4Mrt,
Tg(Pax3-cre)2Joe,
Tg(Pcp2-cre)1Amc,
Tg(Pcp2-cre)2Mpin,
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut,
Tg(Pf4-icre)Q3Rsko,
Tg(Pitx2-cre/Esr1*)#Hmd,
Tg(Pitx3-cre/ERT2)1Yqd,
Tg(Plp1-cre/ERT)3Pop,
Tg(Postn-icre/ERT2)#Wet,
Tg(Prdm1-cre)1Masu,
Tg(Prg4-cre/ERT2)#Ndy,
Tg(Prrx1-cre)1Cjt,
Tg(Rr437-cre)#Hmd,
Tg(rtetR-tetO-cre)1Mhz,
Tg(S100a4-cre)1Egn,
Tg(Scx-cre)HShuk,
Tg(Sim1-cre)1Lowl,
Tg(Slc1a3-cre/ERT2)45-72Fwp,
Tg(Smarcd3-cre/ERT2)#Bbr,
Tg(Tagln-cre)1Her,
Tg(Tagln-cre)1Jjl,
Tg(Tagln-cre)1Jomm,
Tg(Tagln-cre)1Llw,
Tg(Tagln-cre/ERT2)1Feil,
Tg(Tagln-rtTA-cre)1Llw,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Tal1-cre/ERT)42-056Jrg,
Tg(Tbx18-icre)3Fech,
Tg(Tbx1-cre)1Joe,
Tg(Tek-cre)12Flv,
Tg(Tek-cre)1Ywa,
Tg(Tek-cre)5326Sato,
Tg(Tek-icre/ERT2)1Soff,
Tg(Thy1-cre)1Vln,
Tg(Tnni3-cre/GFP)1Mknn,
Tg(Tnnt2-cre)5Blh,
Tg(Vav1-cre)1Awr,
Tg(Vav1-cre)8Cgp,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Wnt11-cre/ERT2)1Jwng,
Tg(Wt1-cre)1Jbeb,
Tg(WT1-cre)AG11Dbdr,
Thtm1(cre)Te,
Tnni3tm1(EGFP/cre/ERT2)Wtsi,
Twist2tm1.1(cre)Dor,
Twist2tm1(cre/ERT2)Eno,
Viptm1(cre)Zjh,
Wt1tm1(EGFP/cre)Wtp,
Wt1tm2(cre/ERT2)Wtp
(less)
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J:309445
Fig. 7
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Recombinase Activity
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References
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Analysis Tools